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A Literature Based Method for Identifying Gene-Disease Connections



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Lada A. Adamic, Dennis M. Wilkinson, Bernardo A. Huberman, Eytan Adar

in Proceedings of CSB2002, Stanford, CA, 14-16 Aug. 2002.

HP Laboratories
Palo Alto, CA 94304

Abstract

We present a statistical method that can swiftly identify, from the literature, sets of genes known to be associated with given diseases. It offers a comprehensive way to treat alias symbols, a statistical method for computing the relevance of the gene to the query, and a novel way to disambiguate gene symbols from other abbreviations. The method is illustrated by finding genes related to breast cancer.

Full paper: (PDF)
Supplementary materials

DEMO (10/17/2002)
search for genes related to any Medical Subject Heading.

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